Transcript: lnc-DLK1-35:55

Basic information

LNCipedia transcript ID: lnc-DLK1-35:55 
HGNC Gene Symbol: lnc-DLK1-35    
HGNC Full Gene Name: maternally expressed 3
Ensembl Gene ID: ENSG00000214548
Ensembl Transcript ID: ENST00000521404
Location (hg38): chr14:100826126-100860989
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 1426 bp
Exons: 6
Sources: Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000521404; ENST00000521404.1; MEG3-013; OTTHUMT00000381045.1; ENST00000521404.5
Alternative gene names: ENSG00000214548; MEG3; ENSG00000214548.8; OTTHUMG00000029052.7; ENSG00000214548.10; ENSG00000214548.14; GTL2; NCRNA00023; LINC00023; onco-lncRNA-83; ENSG00000214548.15


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -66.626 non-coding 
CPAT coding probability 58.91% coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
lnc-DLK1-35:55 no no no no

Available literature

  1. Briese (2016), Whole transcriptome profiling reveals the RNA content of motor axons., Nucleic Acids Res.
  2. Gao (2016), Decreased expression of MEG3 contributes to retinoblastoma progression and affects retinoblastoma cell growth by regulating the activity of Wnt/β-catenin pathway., Tumour Biol.
  3. Ichigozaki (2016), Serum long non-coding RNA, snoRNA host gene 5 level as a new tumor marker of malignant melanoma., Exp. Dermatol.
  4. Kanduri (2016), Long noncoding RNAs: Lessons from genomic imprinting., Biochim. Biophys. Acta
  5. Kato (2016), An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy., Nat Commun
  6. Li (2016), Epigenetic repression of long non-coding RNA MEG3 mediated by DNMT1 represses the p53 pathway in gliomas., Int. J. Oncol.
  7. Liu (2016), The mechanism of adenosine-mediated activation of lncRNA MEG3 and its antitumor effects in human hepatoma cells., Int. J. Oncol.
  8. Rosa (2016), Long Noncoding RNA Regulation of Pluripotency., Stem Cells Int
  9. Su (2016), Skp2 regulates non-small cell lung cancer cell growth by Meg3 and miR-3163., Tumour Biol.
  10. Xie (2016), Long non-coding RNAs in colorectal cancer., Oncotarget


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-DLK1-4:7
3.1 lnc-DLK1-4:8
4.0 MEG3:25
4.1 MEG3:25
5.0 MEG3:25
5.1 lnc-CYP46A1-35:55
5.2 lnc-DLK1-35:55

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