Transcript: PVT1:75
Basic information
LNCipedia transcript ID: PVT1:75
LNCipedia gene ID: PVT1
Location (hg38): chr8:127983898-128010444
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 13144 bp
Exons: 7
Sources: FANTOM CAT (stringent)
Alternative transcript names: ENSG00000249859.3|MICT00000351399.1
Alternative gene names: NCRNA00079; LINC00079; onco-lncRNA-100
RNA sequence:
Structure:
Protein coding potential
| Metric |
Raw result |
Interpretation |
| PRIDE reprocessing 2.0 |
0 |
non-coding |
| Lee translation initiation sites |
|
non-coding |
| PhyloCSF score |
8.1759 |
non-coding |
| CPAT coding probability |
2.32% |
non-coding |
| Bazzini small ORFs |
0 |
non-coding |
In stringent set:
yes
Locus conservation
| Locus conservation? |
 |
 |
 |
 |
| PVT1:75 |
no
|
no
|
no
|
no
|
Available literature
-
Austin
(2017),
Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle.,
J. Allergy Clin. Immunol.
-
Cui
(2016),
Long non-coding RNA PVT1 as a novel biomarker for diagnosis and prognosis of non-small cell lung cancer.,
Tumour Biol.
-
Li
(2016),
Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells.,
Nucleic Acids Res.
-
Zhou
(2016),
Long noncoding RNA PVT1 modulates thyroid cancer cell proliferation by recruiting EZH2 and regulating thyroid-stimulating hormone receptor (TSHR).,
Tumour Biol.
-
Cabanski
(2015),
Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function.,
RNA Biol
-
Colombo
(2015),
PVT1: a rising star among oncogenic long noncoding RNAs.,
Biomed Res Int
-
Ding
(2015),
Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients.,
Oncol Lett
-
Guo
(2015),
Competing endogenous RNA networks and gastric cancer.,
World J. Gastroenterol.
-
Huang
(2015),
Increased expression of the lncRNA PVT1 is associated with poor prognosis in pancreatic cancer patients.,
Minerva Med.
-
Kim
(2015),
MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression.,
Oncotarget
-
Kong
(2015),
Long noncoding RNA PVT1 indicates a poor prognosis of gastric cancer and promotes cell proliferation through epigenetically regulating p15 and p16.,
Mol. Cancer
-
Liu
(2015),
Carboplatin-docetaxel-induced activity against ovarian cancer is dependent on up-regulated lncRNA PVT1.,
Int J Clin Exp Pathol
-
Malouf
(2015),
Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing.,
Mol Oncol
-
Na
(2015),
Long non-coding RNA UCA1 contributes to the progression of prostate cancer and regulates proliferation through KLF4-KRT6/13 signaling pathway.,
Int J Clin Exp Med
-
Pei
(2015),
Notch-1 promotes breast cancer cells proliferation by regulating LncRNA GAS5.,
Int J Clin Exp Med
-
Ragusa
(2015),
Non-coding landscapes of colorectal cancer.,
World J. Gastroenterol.
-
Shih
(2015),
Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism.,
Int J Mol Sci
-
Tantai
(2015),
Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer.,
Int J Clin Exp Pathol
-
Wei
(2015),
Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor.,
Oncotarget
-
Xue
(2015),
Decreased expression of long non-coding RNA NBAT-1 is associated with poor prognosis in patients with clear cell renal cell carcinoma.,
Int J Clin Exp Pathol
-
Younger
(2015),
Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage.,
Nucleic Acids Res.
-
Yu
(2015),
Cardiac hypertrophy is positively regulated by long non-coding RNA PVT1.,
Int J Clin Exp Pathol
-
Zeng
(2015),
Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia.,
J Hematol Oncol
-
Zhang
(2015),
Overexpression of long non-coding RNA PVT1 in gastric cancer cells promotes the development of multidrug resistance.,
Biochem. Biophys. Res. Commun.
-
Zhang
(2015),
Cancer Specific Long Noncoding RNAs Show Differential Expression Patterns and Competing Endogenous RNA Potential in Hepatocellular Carcinoma.,
PLoS ONE
-
Zhou
(2015),
Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer.,
Sci Rep
-
Zhuang
(2015),
Tetracycline-inducible shRNA targeting long non-coding RNA PVT1 inhibits cell growth and induces apoptosis in bladder cancer cells.,
Oncotarget
-
Alaimo
(2014),
ncPred: ncRNA-Disease Association Prediction through Tripartite Network-Based Inference.,
Front Bioeng Biotechnol
-
Athie
(2014),
FAL1ing inside an amplicon.,
Cancer Cell
-
Chinen
(2014),
8q24 amplified segments involve novel fusion genes between NSMCE2 and long noncoding RNAs in acute myelogenous leukemia.,
J Hematol Oncol
-
Ding
(2014),
Expression and clinical significance of the long non-coding RNA PVT1 in human gastric cancer.,
Onco Targets Ther
-
Dryden
(2014),
Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.,
Genome Res.
-
Garzon
(2014),
Expression and prognostic impact of lncRNAs in acute myeloid leukemia.,
Proc. Natl. Acad. Sci. U.S.A.
-
Johnsson
(2014),
Expanding the functional role of long noncoding RNAs.,
Cell Res.
-
Kim
(2014),
Novel fusion transcripts in human gastric cancer revealed by transcriptome analysis.,
Oncogene
-
Li
(2014),
Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets.,
Front Bioeng Biotechnol
-
Paci
(2014),
Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer.,
BMC Syst Biol
-
Perry
(2014),
Role of non-coding RNAs in maintaining primary airway smooth muscle cells.,
Respir. Res.
-
Su
(2014),
Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes.,
Oncotarget
-
Takahashi
(2014),
Amplification of PVT-1 is involved in poor prognosis via apoptosis inhibition in colorectal cancers.,
Br. J. Cancer
-
Tseng
(2014),
PVT1 dependence in cancer with MYC copy-number increase.,
Nature
-
Wan
(2014),
Noncoding RNAs in DNA repair and genome integrity.,
Antioxid. Redox Signal.
-
Wang
(2014),
Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2.,
Hepatology
-
Wang
(2014),
Characteristics of PVT1 and its roles in diseases.,
Chin. Med. Sci. J.
-
Yang
(2014),
A network based method for analysis of lncRNA-disease associations and prediction of lncRNAs implicated in diseases.,
PLoS ONE
-
Yang
(2014),
Increased expression of the lncRNA PVT1 promotes tumorigenesis in non-small cell lung cancer.,
Int J Clin Exp Pathol
-
Zhang
(2014),
Frequent mutation of rs13281615 and its association with PVT1 expression and cell proliferation in breast cancer.,
J Genet Genomics
-
Alvarez
(2013),
Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy.,
PLoS ONE
-
Bisio
(2013),
Identification of new p53 target microRNAs by bioinformatics and functional analysis.,
BMC Cancer
-
Cao
(2013),
Analysis of long non-coding RNA expression profiles in gastric cancer.,
World J. Gastroenterol.
-
Du
(2013),
Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer.,
Nat. Struct. Mol. Biol.
-
Alvarez
(2011),
Functional characterization of the plasmacytoma variant translocation 1 gene (PVT1) in diabetic nephropathy.,
PLoS ONE
-
You
(2011),
Genome-wide screen identifies PVT1 as a regulator of Gemcitabine sensitivity in human pancreatic cancer cells.,
Biochem. Biophys. Res. Commun.
-
Carramusa
(2007),
The PVT-1 oncogene is a Myc protein target that is overexpressed in transformed cells.,
J. Cell. Physiol.
LNCipedia transcript ID history
| LNCipedia version |
LNCipedia transcript ID |
| 4.1 |
PVT1:75 |
| 5.0 |
PVT1:75 |
| 5.1 |
PVT1:75 |
| 5.2 |
PVT1:75 |