Transcript: PVT1:33

Basic information

LNCipedia transcript ID: PVT1:33 
HGNC Gene Symbol: PVT1    
HGNC Full Gene Name: Pvt1 oncogene
Ensembl Gene ID: ENSG00000249859
Ensembl Transcript ID: ENST00000521600
Location (hg38): chr8:127989217-128096578
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA
Transcript size: 408 bp
Exons: 4
Sources: Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000521600; ENST00000521600.1; PVT1-018; OTTHUMT00000380709.1; NONHSAT129074; ENST00000521600.5
Alternative gene names: ENSG00000249859; PVT1; ENSG00000249859.2; OTTHUMG00000164871.1; ENSG00000249859.3; ENSG00000249859.7; NCRNA00079; LINC00079; onco-lncRNA-100; ENSG00000249859.8; ENSG00000249859.9


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -150.5793 non-coding 
CPAT coding probability 2.67% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
PVT1:33 no no no no

Available literature

  1. Austin (2017), Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle., J. Allergy Clin. Immunol.
  2. Cui (2016), Long non-coding RNA PVT1 as a novel biomarker for diagnosis and prognosis of non-small cell lung cancer., Tumour Biol.
  3. Li (2016), Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells., Nucleic Acids Res.
  4. Zhou (2016), Long noncoding RNA PVT1 modulates thyroid cancer cell proliferation by recruiting EZH2 and regulating thyroid-stimulating hormone receptor (TSHR)., Tumour Biol.
  5. Cabanski (2015), Pan-cancer transcriptome analysis reveals long noncoding RNAs with conserved function., RNA Biol
  6. Colombo (2015), PVT1: a rising star among oncogenic long noncoding RNAs., Biomed Res Int
  7. Ding (2015), Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients., Oncol Lett
  8. Guo (2015), Competing endogenous RNA networks and gastric cancer., World J. Gastroenterol.
  9. Huang (2015), Increased expression of the lncRNA PVT1 is associated with poor prognosis in pancreatic cancer patients., Minerva Med.
  10. Kim (2015), MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression., Oncotarget


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-MYC-2:24
3.1 lnc-MYC-2:24
4.0 PVT1:33
4.1 PVT1:33
5.0 PVT1:33
5.1 PVT1:33
5.2 PVT1:33

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