Transcript: MYCNOS:6

Basic information

LNCipedia transcript ID: MYCNOS:6 
HGNC Gene Symbol: MYCNOS    
HGNC Full Gene Name: MYCN opposite strand
Ensembl Gene ID: ENSG00000233718
Ensembl Transcript ID: ENST00000641387
Location (hg38): chr2:15940121-15941238
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 496 bp
Exons: 2
Sources: Biogazelle lncRNA chip; Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000439180; ENST00000439180.1; MYCNOS-004; OTTHUMT00000267898.1; NONHSAT069306; ENST00000641387.1
Alternative gene names: ENSG00000233718; MYCNOS; ENSG00000233718.1; OTTHUMG00000151741.1; ENSG00000233718.5; NCYM; N-CYM; MYCN-AS1; ENSG00000233718.7


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score -470.734 non-coding 
CPAT coding probability 5.27% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: yes

Locus conservation

Locus conservation?
MYCNOS:6 yes no no no

Available literature

  1. Vadie (2015), MYCNOS functions as an antisense RNA regulating MYCN., RNA Biol
  2. Suenaga (2014), NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas., PLoS Genet.
  3. Armstrong (1992), Isolation and characterization of complementary DNA for N-cym, a gene encoded by the DNA strand opposite to N-myc., Cell Growth Differ.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-NBAS-4:5
3.1 lnc-NBAS-4:5
4.0 MYCNOS:6
4.1 MYCNOS:6
5.0 MYCNOS:6
5.1 MYCNOS:6
5.2 MYCNOS:6