Transcript: MYCNOS:1

Basic information

LNCipedia transcript ID: MYCNOS:1 
HGNC Gene Symbol: MYCNOS    
HGNC Full Gene Name: MYCN opposite strand
Ensembl Gene ID: ENSG00000233718
Ensembl Transcript ID: ENST00000641534
Location (hg38): chr2:15940185-15942249
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 389 bp
Exons: 3
Sources: Biogazelle lncRNA chip; Ensembl release 64 - Sep 2011; Gencode v13; Ensembl release 68 - Jul 2012; NONCODE v4; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000448719; ENST00000448719.1; MYCNOS-003; OTTHUMT00000267897.1; NONHSAT069307; ENST00000641534.1
Alternative gene names: ENSG00000233718; MYCNOS; ENSG00000233718.1; OTTHUMG00000151741.1; ENSG00000233718.5; NCYM; N-CYM; MYCN-AS1; ENSG00000233718.7


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score 50.3144 non-coding 
CPAT coding probability 0.15% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
MYCNOS:1 yes no no no

Available literature

  1. Vadie (2015), MYCNOS functions as an antisense RNA regulating MYCN., RNA Biol
  2. Suenaga (2014), NCYM, a Cis-antisense gene of MYCN, encodes a de novo evolved protein that inhibits GSK3β resulting in the stabilization of MYCN in human neuroblastomas., PLoS Genet.
  3. Armstrong (1992), Isolation and characterization of complementary DNA for N-cym, a gene encoded by the DNA strand opposite to N-myc., Cell Growth Differ.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
1.3 lnc-NBAS-4:1
3.1 lnc-NBAS-4:1
4.0 MYCNOS:1
4.1 MYCNOS:1
5.0 MYCNOS:1
5.1 MYCNOS:1
5.2 MYCNOS:1