Transcript: KCNQ1OT1:5

Basic information

LNCipedia transcript ID: KCNQ1OT1:5 
HGNC Gene Symbol: KCNQ1OT1    
HGNC Full Gene Name: KCNQ1 opposite strand/antisense transcript 1
Ensembl Gene ID: ENSG00000269821
Ensembl Transcript ID: ENST00000597346
Location (hg38): chr11:2608328-2699994
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 91667 bp
Exons: 1
Sources: Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000597346.1
Alternative gene names: ENSG00000269821.1; KCNQ1OT1; KvDMR1; KCNQ1-AS2; KvLQT1-AS; LIT1; NCRNA00012


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 1 coding 
Peptide Confidence Reading frame
RSIQNCINKWK 90.9090909090909% sense-3
Lee translation initiation sites 0 non-coding 
PhyloCSF score 43.7905 non-coding 
CPAT coding probability 14.92% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
KCNQ1OT1:5 no no no no

Available literature

  1. Kanduri (2016), Long noncoding RNAs: Lessons from genomic imprinting., Biochim. Biophys. Acta
  2. Liu (2016), The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster., Nucleic Acids Res.
  3. Miano (2016), Luminal long non-coding RNAs regulated by estrogen receptor alpha in a ligand-independent manner show functional roles in breast cancer., Oncotarget
  4. Zhang (2016), Long non-coding RNA chromogenic in situ hybridisation signal pattern correlation with breast tumour pathology., J. Clin. Pathol.
  5. Bao (2015), The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters., Cell Res.
  6. Cajigas (2015), Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling., Development
  7. Chen (2015), Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity., Sci Rep
  8. Chen (2015), Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA., Sci Rep
  9. Engelhardt (2015), Evolution of the unspliced transcriptome., BMC Evol. Biol.
  10. Fan (2015), Long non-coding RNA ROR decoys gene-specific histone methylation to promote tumorigenesis., Genome Biol.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-CDKN1C-3:5
4.0 KCNQ1OT1:5
4.1 KCNQ1OT1:5
5.0 KCNQ1OT1:5
5.1 KCNQ1OT1:5
5.2 KCNQ1OT1:5

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