Transcript: EGFR-AS1:2

Basic information

LNCipedia transcript ID: EGFR-AS1:2 
HGNC Gene Symbol: EGFR-AS1    
HGNC Full Gene Name: EGFR antisense RNA 1
Ensembl Gene ID: ENSG00000224057
Ensembl Transcript ID: ENST00000442411
Location (hg38): chr7:55179750-55188934
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA
Transcript size: 2806 bp
Exons: 2
Sources: Gencode v13; Ensembl release 68 - Jul 2012; Ensembl release 75 - Feb 2014; Ensembl release 83 - Dec 2015; Ensembl release 87 - Dec 2016; Ensembl release 90 - Aug 2017; Ensembl release 92 - Apr 2018
Alternative transcript names: ENST00000442411.1; RP5-1091E12.1-001; OTTHUMT00000343091.1
Alternative gene names: ENSG00000224057.1; RP5-1091E12.1; OTTHUMG00000156126.1; EGFR-AS1;


RNA sequence:

Structure:

Protein coding potential

Metric Raw result Interpretation
PRIDE reprocessing 2.0 0 non-coding 
Lee translation initiation sites 0 non-coding 
PhyloCSF score 133.928 coding 
CPAT coding probability 13.30% non-coding 
Bazzini small ORFs 0 non-coding 

In stringent set: no

Locus conservation

Locus conservation?
EGFR-AS1:2 yes no no no

Available literature

  1. Tan (2017), Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma., Nat. Med.
  2. Qi (2016), The long noncoding RNA, EGFR-AS1, a target of GHR, increases the expression of EGFR in hepatocellular carcinoma., Tumour Biol.


LNCipedia transcript ID history

LNCipedia version LNCipedia transcript ID
3.1 lnc-VOPP1-1:1
4.0 EGFR-AS1:2
4.1 EGFR-AS1:2
5.0 EGFR-AS1:2
5.1 EGFR-AS1:2
5.2 EGFR-AS1:2