Gene: TUG1

Basic information

LNCipedia gene ID: TUG1 
Location (hg38): chr22:30969158-30985225
Strand: +
Class: intergenic
Sequence Ontology term: lincRNA_gene
Transcripts: 76

Transcripts

Transcript IDLocation (hg38)Length
TUG1:1 chr22:30969158-30973592 3191 bp
TUG1:10 chr22:30969648-30979391 7101 bp
TUG1:11 chr22:30969648-30979312 7153 bp
TUG1:12 chr22:30969657-30978845 6477 bp
TUG1:13 chr22:30969712-30979396 7167 bp
TUG1:14 chr22:30969712-30979396 7028 bp
TUG1:15 chr22:30969712-30979396 8117 bp
TUG1:16 chr22:30969712-30979396 8103 bp
TUG1:17 chr22:30969712-30979396 8541 bp
TUG1:18 chr22:30969761-30979275 6829 bp
TUG1:19 chr22:30970677-30976063 2744 bp
TUG1:2 chr22:30969158-30973592 3291 bp
TUG1:20 chr22:30971048-30973428 1237 bp
TUG1:21 chr22:30971066-30978845 5123 bp
TUG1:22 chr22:30971066-30979395 5673 bp
TUG1:23 chr22:30971352-30973549 1248 bp
TUG1:24 chr22:30971367-30978845 4892 bp
TUG1:25 chr22:30971367-30976063 2110 bp
TUG1:26 chr22:30971422-30976005 1758 bp
TUG1:27 chr22:30971439-30973356 968 bp
TUG1:28 chr22:30971480-30973109 386 bp
TUG1:29 chr22:30971745-30973245 416 bp
TUG1:3 chr22:30969211-30979394 7541 bp
TUG1:30 chr22:30971926-30973612 1005 bp
TUG1:31 chr22:30972045-30979351 5057 bp
TUG1:32 chr22:30972263-30979391 5561 bp
TUG1:33 chr22:30972263-30976063 2233 bp
TUG1:34 chr22:30972901-30976081 1599 bp
TUG1:35 chr22:30973412-30975479 443 bp
TUG1:36 chr22:30969223-30973083 393 bp
TUG1:37 chr22:30969223-30979450 7502 bp
TUG1:38 chr22:30969223-30979450 7585 bp
TUG1:39 chr22:30969223-30985225 15053 bp
TUG1:4 chr22:30969211-30979394 7597 bp
TUG1:40 chr22:30969223-30985225 15053 bp
TUG1:41 chr22:30969269-30972938 695 bp
TUG1:42 chr22:30969269-30979386 5568 bp
TUG1:43 chr22:30969269-30979450 7863 bp
TUG1:44 chr22:30969269-30979450 7435 bp
TUG1:45 chr22:30969269-30985225 13143 bp
TUG1:46 chr22:30969490-30979405 8348 bp
TUG1:47 chr22:30969490-30979405 7652 bp
TUG1:48 chr22:30969490-30979405 5688 bp
TUG1:49 chr22:30969490-30979450 4968 bp
TUG1:5 chr22:30969211-30979394 7527 bp
TUG1:50 chr22:30969490-30979450 7589 bp
TUG1:51 chr22:30970656-30976063 2765 bp
TUG1:52 chr22:30972466-30976063 2030 bp
TUG1:53 chr22:30972466-30979460 5413 bp
TUG1:54 chr22:30972466-30979460 5427 bp
TUG1:55 chr22:30972890-30976081 1610 bp
TUG1:56 chr22:30969211-30979395 7542 bp
TUG1:57 chr22:30969211-30979395 7598 bp
TUG1:58 chr22:30969211-30979395 7528 bp
TUG1:59 chr22:30969245-30971483 375 bp
TUG1:6 chr22:30969243-30979208 7240 bp
TUG1:60 chr22:30969269-30978843 4650 bp
TUG1:61 chr22:30969270-30979395 7469 bp
TUG1:62 chr22:30969272-30978578 4214 bp
TUG1:63 chr22:30969278-30978831 4449 bp
TUG1:64 chr22:30969295-30976022 1817 bp
TUG1:65 chr22:30969472-30978848 5017 bp
TUG1:66 chr22:30969853-30975997 3419 bp
TUG1:67 chr22:30969932-30974103 3028 bp
TUG1:68 chr22:30969959-30978824 6154 bp
TUG1:69 chr22:30970094-30976058 3308 bp
TUG1:7 chr22:30969244-30979396 6716 bp
TUG1:70 chr22:30970182-30978847 7084 bp
TUG1:71 chr22:30970302-30978819 5875 bp
TUG1:72 chr22:30970690-30978823 5412 bp
TUG1:73 chr22:30970758-30976039 4207 bp
TUG1:74 chr22:30971064-30976114 2787 bp
TUG1:75 chr22:30971197-30973372 932 bp
TUG1:76 chr22:30971439-30978722 4752 bp
TUG1:8 chr22:30969276-30979341 5016 bp
TUG1:9 chr22:30969277-30979341 7422 bp


Locus conservation

Locus conservation?
TUG1 no no no no

Available literature

  1. Wang (2017), Long non-coding RNA TUG1 promotes migration and invasion by acting as a ceRNA of miR-335-5p in osteosarcoma cells., Cancer Sci.
  2. Lennox (2016), Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides., Nucleic Acids Res.
  3. Ma (2016), Upregulation of long non-coding RNA TUG1 correlates with poor prognosis and disease status in osteosarcoma., Tumour Biol.
  4. Cai (2015), The long noncoding RNA TUG1 regulates blood-tumor barrier permeability by targeting miR-144., Oncotarget
  5. Hu (2015), Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus., Genes Dev.
  6. Huang (2015), Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2., Mol. Cancer
  7. Imam (2015), The lncRNA NRON modulates HIV-1 replication in a NFAT-dependent manner and is differentially regulated by early and late viral proteins., Sci Rep
  8. Liu (2015), Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells., J. Neurooncol.
  9. Pastori (2015), The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation., Proc. Natl. Acad. Sci. U.S.A.
  10. Sugihara (2015), Noncoding RNA Expression Aberration Is Associated with Cancer Progression and Is a Potential Biomarker in Esophageal Squamous Cell Carcinoma., Int J Mol Sci
  11. Tan (2015), Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cells., FEBS Lett.
  12. Wang (2015), Identification of lncRNA-associated competing triplets reveals global patterns and prognostic markers for cancer., Nucleic Acids Res.
  13. Wang (2015), The mitotic regulator Hec1 is a critical modulator of prostate cancer through the long non-coding RNA BX647187 in vitro., Biosci. Rep.
  14. Xu (2015), Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma., Tumour Biol.
  15. Yin (2015), Downregulation of lncRNA TUG1 affects apoptosis and insulin secretion in mouse pancreatic β cells., Cell. Physiol. Biochem.
  16. Gezer (2014), Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes., Cell Biol. Int.
  17. Isin (2014), Investigation of circulating lncRNAs in B-cell neoplasms., Clin. Chim. Acta
  18. Li (2014), Discovery of Protein-lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets., Front Bioeng Biotechnol
  19. Michalik (2014), Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth., Circ. Res.
  20. Puvvula (2014), Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit., Nat Commun
  21. Roberts (2014), The role of long non-coding RNAs in neurodevelopment, brain function and neurological disease., Philos. Trans. R. Soc. Lond., B, Biol. Sci.
  22. Wan (2014), Noncoding RNAs in DNA repair and genome integrity., Antioxid. Redox Signal.
  23. Zhang (2014), P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression., Cell Death Dis
  24. van Heesch (2014), Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes., Genome Biol.
  25. Cao (2013), Analysis of long non-coding RNA expression profiles in gastric cancer., World J. Gastroenterol.
  26. Chen (2013), Novel human lncRNA-disease association inference based on lncRNA expression profiles., Bioinformatics
  27. Han (2013), Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder., J Surg Oncol
  28. Kapusta (2013), Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs., PLoS Genet.
  29. Liu (2013), WITHDRAWN: Down-regulation of long non-coding RNA TUG1 suppresses melanoma cell proliferation and induces apoptosis via up-regulating microRNA-9., Biochem. Biophys. Res. Commun.
  30. Liu (2013), Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA., RNA
  31. Sauvageau (2013), Multiple knockout mouse models reveal lincRNAs are required for life and brain development., Elife
  32. Wan (2013), Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway., Cell. Signal.
  33. Zhang (2013), Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis., Asian Pac. J. Cancer Prev.
  34. Özgür (2013), Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells., Clin. Exp. Med.
  35. Clark (2012), Genome-wide analysis of long noncoding RNA stability., Genome Res.
  36. Jalali (2012), Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs., Biol. Direct
  37. Johnson (2012), Long non-coding RNAs in Huntington's disease neurodegeneration., Neurobiol. Dis.
  38. Kelley (2012), Transposable elements reveal a stem cell-specific class of long noncoding RNAs., Genome Biol.
  39. Tani (2012), Genome-wide determination of RNA stability reveals hundreds of short-lived noncoding transcripts in mammals., Genome Res.
  40. Friedel (2009), Conserved principles of mammalian transcriptional regulation revealed by RNA half-life., Nucleic Acids Res.
  41. Guttman (2009), Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals., Nature
  42. Khalil (2009), Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression., Proc. Natl. Acad. Sci. U.S.A.
  43. Young (2005), The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina., Curr. Biol.