Gene: HOTAIR

Basic information

HGNC Gene Symbol: HOTAIR  ?
HGNC Full Gene Name: HOX transcript antisense RNA
Location (hg38): chr12:53962308-53974956
Strand: -
Class: antisense
Sequence Ontology term: antisense_lncRNA_gene
Transcripts: 11

Transcripts

Transcript IDLocation (hg38)Length
HOTAIR:1 chr12:53962308-53974956 2421 bp
HOTAIR:10 chr12:53963802-53966630 572 bp
HOTAIR:11 chr12:53962626-53966193 685 bp
HOTAIR:2 chr12:53962308-53974956 2368 bp
HOTAIR:3 chr12:53963749-53974947 918 bp


Locus conservation

Locus conservation?
HOTAIR yes no no no

Available literature

  1. Botti (2017), LncRNA HOTAIR as Prognostic Circulating Marker and Potential Therapeutic Target in Patients with Tumor Diseases., Curr Drug Targets
  2. Bayram (2016), A functional HOTAIR rs12826786 C>T polymorphism is associated with breast cancer susceptibility and poor clinicopathological characteristics in a Turkish population: a hospital-based case-control study., Tumour Biol.
  3. Bhan (2016), Estradiol-Induced Transcriptional Regulation of Long Non-Coding RNA, HOTAIR., Methods Mol. Biol.
  4. Chang (2016), Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin., Mol Med Rep
  5. Choudhry (2016), Hypoxic regulation of the noncoding genome and NEAT1., Brief Funct Genomics
  6. Fang (2016), Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells., Lab. Invest.
  7. Fayda (2016), Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?, Tumour Biol.
  8. Fu (2016), Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways., Oncotarget
  9. Gao (2016), ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer., Oncotarget
  10. Jiang (2016), The long non-coding RNA HOTAIR affects the radiosensitivity of pancreatic ductal adenocarcinoma by regulating the expression of Wnt inhibitory factor 1., Tumour Biol.


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